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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
24.24
Human Site:
Y535
Identified Species:
48.48
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
Y535
T
M
W
E
A
L
S
Y
G
Q
K
P
Y
K
K
Chimpanzee
Pan troglodytes
XP_515637
619
69840
Y535
T
M
W
E
A
L
S
Y
G
Q
K
P
Y
K
K
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
Y535
T
M
W
E
A
L
S
Y
G
Q
K
P
Y
K
K
Dog
Lupus familis
XP_861301
601
68596
L527
D
V
W
S
F
G
V
L
M
W
E
A
F
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
Y534
T
M
W
E
A
F
S
Y
G
Q
K
P
Y
K
K
Rat
Rattus norvegicus
Q64725
629
71510
L555
D
V
W
S
F
G
V
L
M
W
E
A
F
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
R438
R
K
G
V
Y
K
M
R
K
K
Q
I
D
V
A
Chicken
Gallus gallus
Q07494
984
109166
F820
V
M
W
E
V
M
S
F
G
E
R
P
Y
W
D
Frog
Xenopus laevis
Q91736
902
100832
Y738
V
M
W
E
V
M
S
Y
G
E
R
P
Y
W
D
Zebra Danio
Brachydanio rerio
O13146
981
109636
Y825
V
M
W
E
V
I
S
Y
G
E
R
P
Y
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
L863
T
I
W
E
M
F
S
L
G
A
P
P
Y
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
Y669
T
L
W
E
A
L
S
Y
G
K
R
P
Y
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
6.6
N.A.
0
46.6
53.3
53.3
N.A.
46.6
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
26.6
N.A.
13.3
73.3
73.3
80
N.A.
60
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
42
0
0
0
0
9
0
17
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
0
0
0
0
9
0
17
% D
% Glu:
0
0
0
75
0
0
0
0
0
25
17
0
0
0
17
% E
% Phe:
0
0
0
0
17
17
0
9
0
0
0
0
17
0
0
% F
% Gly:
0
0
9
0
0
17
0
0
75
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
9
17
34
0
0
34
34
% K
% Leu:
0
9
0
0
0
34
0
25
0
0
0
0
0
0
0
% L
% Met:
0
59
0
0
9
17
9
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
75
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
34
9
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
0
0
34
0
0
0
0
% R
% Ser:
0
0
0
17
0
0
75
0
0
0
0
0
0
17
9
% S
% Thr:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
25
17
0
9
25
0
17
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
92
0
0
0
0
0
0
17
0
0
0
25
0
% W
% Tyr:
0
0
0
0
9
0
0
59
0
0
0
0
75
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _